Materials, Electrode Placement and Signal Collection
Electrode Type
We use stretchable dry Ag/AgCl electrodes, embedded directly into the PU substrate, because they offer the best balance of signal quality and real-world wearability for gut–brain monitoring.


Electrode Placement
We place electrodes over three gut “hubs” that most strongly talk to the brain (with the most microbiome): the colon, distal small intestine, and stomach. Channels over the colon track motility where dense microbiota ferment fiber into short-chain fatty acids that can reach the brain and modulate inflammation and barrier integrity. Channels over the distal small intestine capture microbiome-tuned serotonin and gut-hormone signals from enterochromaffin and enteroendocrine cells, while stomach channels read out vagal and hormonal cues such as ghrelin that shape hunger, stress, and reward.
Kalman Filtering
Kalman Filtering is used for artifact rejection
